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This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 12, Issue 6 pp 4866—4878
MiR-519d targets HER3 and can be used as a potential serum biomarker for non-small cell lung cancer
Figure 7. MiR-519d suppresses PI3K/AKT pathway via targeting HER3. Western blot analyses (A) and statistical analysis (B) demonstrated that the overexpression of miR-519d significantly inhibited the phosphorylation of PI3K and AKT. (C) Suppression of miR-519d enhanced the phosphorylation of PI3K and AKT, but these effects could largely be reversed by silencing HER3. (D) Statistical analysis. *p<0.05 vs. control, **p<0.01 vs. control, ***p<0.001 vs. control.