Figure 6 — The lncRNA ENSG00000254041.1 promotes cell invasiveness and associates with poor prognosis of pancreatic ductal adenocarcinoma

Research Paper|Volume 12, Issue 4|pp. 3647–3661

The lncRNA ENSG00000254041.1 promotes cell invasiveness and associates with poor prognosis of pancreatic ductal adenocarcinoma

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Figure 6.ENSG00000254041.1 increase the chemoresistance of PC cells to gemcitabine in vitro. (A) GSEA analysis revealed that ENSG00000254041.1 expression associated with the multi-drug resistance. (B) Knockdown of ENSG00000254041.1 decreased the IC₅₀ values of GEM in SW1990 and BxPC-3 cells, and overexpression of ENSG00000254041.1 in Panc-1 cells increased the IC₅₀ values of GEM. ***p < 0.001 compared with indicated group.