Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both <i>in vivo</i> and <i>in vitro</i> models of Parkinson's disease

Chao Guo; Junrong Zhu; Jingwen Wang; Jialin Duan; Shanbo Ma; Ying Yin; Wei Quan; Wei Zhang; Yue Guan; Yi Ding; Aidong Wen; Yingdong Zhang

doi:doi:10.18632/aging.102394

← Back

Research Paper Volume 11, Issue 21 pp 9424—9441

Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

Figure 1. PCA improved behavioral deficits in MPTP- intoxicated mice. (A) Rotarod test in each group. (B) Pole test in each group. Data were expressed as mean ± S.D., n = 12; ^**P< 0.01vs. control group, ^#P< 0.05 vs. MPTP group.