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Research Paper Volume 11, Issue 21 pp 9348—9368

Fructus Ligustri Lucidi preserves bone quality through the regulation of gut microbiota diversity, oxidative stress, TMAO and Sirt6 levels in aging mice

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Figure 2. Fructus Ligustri Lucidi (FLL) preserves the bone microarchitecture and bone strength in the femurs of aging mice. Representative 3D reconstructions of trabecular images in the femoral metaphysis by micro(μ)-CT (A). μCT-derived quantification data of femoral metaphysis including BV/TV (%, B), Tb.N (1/mm) (C), Tb.Sp (mm) (D), Tb.Th (mm) (E), Tt.Ar (mm2) (F), Ct.Ar (mm2) (G), Ct.Th (mm, H). Three-point bending examination results including ultimate load (I), bending strength (X100MPa, J), and elastic modulus (X100GPa, K) in the femurs. Data are presented as mean ± SD. # compared with the normal group. * compared with the aging model group. p < 0.05 was considered statistical difference, n = 8.