Research Paper Volume 11, Issue 17 pp 7257—7273

Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer’s disease

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Figure 8. TLR2 deficiency resulted in neuronal loss in mouse brains. (A, B) Neuronal density detection and quantification analysis indicated a lower capacity of NeuN+ cells in AD, TLR2KO, and AD-TLR2KO mice when compared with WT mice (n=6 for each group, p<0.05).