Figure 3 — Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer

Research Paper|Volume 11, Issue 18|pp. 7442–7456

Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer

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Figure 3.FOXA1 analysis in breast cancer (Oncomine database). The online Oncomine analysis tool (red: overexpression, blue: down-expression) was used to compare FOXA1 expression levels in breast cancer specimens with matched normal specimens. The thresholds for significant probes for each microarray dataset included a two-fold difference in expression between cancer and normal samples and P < 0.0001. The box plot compares FOXA1 expression in cancer samples (right) and matches normal (left) samples generated from the Oncomine database.