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Research Paper|Volume 11, Issue 11|pp. 3574–3584
TGF-β mediates aortic smooth muscle cell senescence in Marfan syndrome
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Figure 6
Figure 6.Proposed mechanisms for TGF-β1-induced VSMC senescence. This study shows that TGF-β1 induces VSMC senescence through activation of ROS/NF-κB signaling, which leads to aortic aneurysm formation in MFS patients.