Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress

Jessica R. Santos-Parker; Talia R. Strahler; Candace J. Bassett; Nina Z. Bispham; Michel B. Chonchol; Douglas R. Seals

doi:doi:10.18632/aging.101149

← Back

Research Paper Volume 9, Issue 1 pp 187—208

Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress

Figure 5. Forearm blood flow (FBF) area under the dose-response curve (AUC) in response to acetylcholine (FBF_ACh) without (-) or with (+) vitamin C (vitC; left) and oxidative stress-mediated suppression of endothelium-dependent dilation (EDD; right) at week 0 and after 12 weeks of placebo or curcumin supplementation. Data are mean±SE; *P<0.05 vs. corresponding group week FBF_ACh (left); Group by time P=0.03, *P=0.02 vs. curcumin week 0 (right).