Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress

Jessica R. Santos-Parker; Talia R. Strahler; Candace J. Bassett; Nina Z. Bispham; Michel B. Chonchol; Douglas R. Seals

doi:doi:10.18632/aging.101149

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Research Paper Volume 9, Issue 1 pp 187—208

Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress

Figure 2. Forearm blood flow (FBF) in response to increasing doses (left and middle) and area under the dose-response curve (AUC; right) to acetylcholine (FBF_ACh) at week 0 and after 12 weeks of placebo or curcumin supplementation. Data are mean±SE; FAV, forearm volume; Group by time P=0.02, *P=0.03 vs. curcumin week 0.