Aging
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Figure 2
Figure 2.Sirt1 regulates NO production. Sirt1 regulates endothelial NO synthase (eNOS) at both the transcriptional and post-transcriptional levels via deacetylation, resulting in the generation of NO for vascular protection. NO also positively regulates Sirt1.
Figure 2 — The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis | Aging