Research Paper Volume 8, Issue 10 pp 2392—2406

Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice

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Figure 7. (A) and (B) Immunohistochemical staining of p16 in the pancreata from 25-week-old control and COX2 transgenic littermates (magnification x20). (C) and (D) Immunohistochemical staining of phospho-H2AX in the pancreata from 23-week-old control and COX2 transgenic littermates (magnification x20). (E) and (F) Immunohistochemical staining of phospho-H2AX in the skin from 25-week-old control and COX2 transgenic littermates (magnification x20). Scale bar=100 μm