Research Paper Volume 8, Issue 10 pp 2370—2391
A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated
Figure 6. Younger males, but not females, performed better than older mice on the rotarod test. (A) Rotarod performance varied among female mice of all age groups. (B) 4-month -old males stayed on the rotarod longer than 28 and 32-month -old males (p = 0.042 and p = 0.006, respectively). Post-hoc tests subject to Bonferroni correction for multiple comparisons. Rotarod sample size: Females n = 20, 20, 26 and 27 for 4, 20, 28 and 32 months; Males n = 22, 20, 30 and 24 for 4, 20, 28 and 32 months.