Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study

Jacob J.E. J.E. Koopman; Jeroen Pijpe; Stefan Böhringer; David van van Bodegom; Ulrika K. K. Eriksson; Hernando Sanchez-Faddeev; Juventus B. B. Ziem; Bas Zwaan; P. Eline Eline Slagboom; Peter de de Knijff; Rudi G.J. G.J. Westendorp

doi:doi:10.18632/aging.100986

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Research Paper Volume 8, Issue 7 pp 1364—1374

Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study

Figure 3. Manhattan plots assessing the associations of SNPs with fertility in women. (A) Manhattan plot assessing the associations of SNPs with observed fertility in middle-aged women of fertile ages from 20 through 44 years. The level of significance is 1.61 × 10⁻⁵, indicated by the red line. (B) Manhattan plot assessing the associations of SNPs with reported fertility in postmenopausal women aged 45 years and older. The level of significance is 1.23 × 10⁻⁵, indicated by the red line.