Telomerase and estrogen-sensing activities are essential for continued mammary growth <i>in vivo</i> but dispensable for “reprogramming” neural stem cells

Andrea L. L. George; Corinne A. A. Boulanger; Gilbert H. H. Smith

doi:doi:10.18632/aging.100985

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Research Paper Volume 8, Issue 7 pp 1353—1362

Telomerase and estrogen-sensing activities are essential for continued mammary growth in vivo but dispensable for “reprogramming” neural stem cells

Figure 3. Senescent outgrowths contain PR⁺ cells but lack ER-α⁺ signaling cells. Immunohistochemical staining of a cross-section from Wap-Cre/TGF-β1⁺ outgrowths stained for ER-α and progesterone receptor (PR). Arrows denote PR positive cells. Scale bars: 40 μm left panels, 80μm right panels.