Research Paper Volume 8, Issue 5 pp 977—985
Defects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis
Figure 5. The impact of MAP1S on the levels of pyroptosis in HK2 cells. (A-D) Representative immunoblot images (A,C) and plots (B,D) showing the impact of MAP1S suppression (A,B) or overexpression (C,D) on the levels of caspase 1 (P10) in the absence (None) or presence of bafilomycin A1 (BAF). Bars in panels (B,D) represent mean ± standard deviation of levels of caspase 1 P10 between different groups. Significance is estimated as described above.