Research Paper Volume 8, Issue 5 pp 917—931
The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks
Figure 4. Modularity coefficients per conditional mutual information network at each treatment level were calculated and genes were assigned to clusters according to their mutual information. (A) Changes of clusters across CR level and colored for clusters found at 12AL. (B) Modularity coefficient for each CMI network at each CR level. (C) CMI networks colored according to clusters identified at each CR level. Edges between genes with strong CMI are colored in black, those with weak CMI in light grey. 24AL, 12AL, 10CR, 20CR, 30CR and 40CR refer respectively to 24h ad libitum feeding per day, 12h ad libitum feeding per day, 10 %, 20 %, 30 % and 40 % restriction.