Research Paper Volume 8, Issue 4 pp 642—661

The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways

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Figure 4. The hunger signaling pathway constructed in the IPA program colored according to genes correlating with circulating leptin levels. Red indicates a positive correlation coefficient and green indicates a negative correlation coefficient. Intensity of the color is related to the strength of the correlation.