Research Paper Volume 7, Issue 12 pp 1171—1182

DNA repair in species with extreme lifespan differences

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Figure 3. Pathway activation strength (PAS) for DNA repair signaling pathways. PAS values for DNA repair pathways in human vs. mouse and NMR vs. mouse (p < 0.05). Positive PAS values reflect upregulated signaling pathways in human or NMR compared with mouse, and negative values represent down-regulated pathways. PAS scores of zero indicate similarly acting pathways in mouse compared with human or NMR.