Figure 2 — Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning

Research Paper|Volume 7, Issue 12|pp. 1198–1211

Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning

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Figure 2.Causal scenarios that might explain the significant genetic correlations between epigenetic age, neuropathology and cognitive declineGenetic variants form a causal anchor that affect biological age (and associated measures such as epigenetic age) and various measures of neuropathology and cognitive decline.