Research Paper Volume 6, Issue 12 pp 1019—1032
The suppression of ghrelin signaling mitigates age-associated thermogenic impairment
Figure 1. Ghrelin and obestatin exhibit differential effects on UCP1 expression in differentiated brown adipocyte HIB1B cells. UCP1 expression in HIB1B cells treated with saline or different concentrations of ghrelin (A), des-acyl ghrelin, DAG (B), and obestatin (C). Summary of UCP1 expression in HIB1B cells treated with saline, 1 nM ghrelin, 10 nM DAG, or 10 nM obestatin (D). N = 9, and each assay was measured in triplicate. *p<0.05, Treatments vs. Controls.