Figure 4.Life span extension through fibrates is NHR-49/PPARalpha-dependentA Life span analyses with several hundred nhr-49 knockout nematodes (variation ok2165, strain RB1716) at 10 micromolar bezafibrate, clofibrate, and fenofibrate versus control (0.1% DMSO). B Life span analyses with several hundred nhr-49 knockout nematodes (variation gk405, strain VC870) at 10 micromolar bezafribrate, clofibrate, and fenofibrate versus control (0.1% DMSO).
