Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner
Figure 2.Clofibrate extends lifespan of adult C. elegans. Life span analyses with several hundred N2 wild type nematodes each at three different concentrations of clofibrate (0.1, 1, and 10 micromolar) versus control (0.1% DMSO).