Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner
Figure 1.Bezafibrate extends lifespan of adult C. elegans. Life span analyses with several hundred N2 wild type nematodes each at three different concentrations of bezafibrate (0.1, 1, and 10 micromolar) versus control (0.1% DMSO).