Research Perspective Volume 5, Issue 3 pp 144—150

The sirtuins, oxidative stress and aging: an emerging link

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Figure 3. Aging and Mitohormesis. Theoretical curve showing how low doses of a stressor may have beneficial effects by activating intracellular stress response pathways. If the stressor exceeds the capacity of the stress response system to maintain homeostasis, then deleterious phenotypes are observed.