Figure 3. A time window for cardiac regeneration. Whole hearts and magnifications at the infarction areas are shown on day P28.5 following LAD ligation of newborn mice at P1.5 and LAD ligation in mice at P7.5 after birth. Images are representative of 6 mice analyzed. Note the complete regeneration of the infarction zone when mice received LAD-ligation on P1.5, whereas no regeneration was seen when mice were LAD-ligated on day P7.5.