Figure 2 — New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis

Research Paper|Volume 4, Issue 10|pp. 715–722

New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53^−/− mice by delaying carcinogenesis

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Figure 2.Rapatar increases lifespan in p53^−/− mice. Mice received Rapatar at 0.5 mg/kg via gavage according to the schedule described in Materials and Methods. Rapatar increased lifespan from 23 to 31 weeks (p<0.001, Mantel-Cox log-rank test).