Research Paper Volume 4, Issue 9 pp 648—659
Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity
Figure 6. Increased IL-21 secretion in aged subjects correlates with Cytomegalovirus (CMV) seropositivity. A. Dot blot depicts the level of IL-21 in aged and young plasma. Data is mean of 60 aged and 60 young subjects. Each dot represents one different subject. B. Dot blot depicts the level of CMV seropositivity in aged and young plasma. Data is mean of 50 aged and 50 young subjects. Each dot represents one different subject. C. Dot blot depicts the level of IL-21 in plasma of CMV+ and CMV- individuals. Data is mean of 38 CMV+ and 48 CMV- subjects. Each dot represents one different subject. D. Dot blot depicts the level of IL-21 in plasma of CMV+ and CMV- aged individuals. Data is mean of 32 CMV+ and 18 CMV- aged subjects. Each dot represents one different subject. E. Dot blot depicts the level of IL-21 in plasma of CMV+ and CMV- young individuals. Data is mean of 6 CMV+ and 30 CMV- young subjects. Each dot represents one different subject.