Research Paper Volume 4, Issue 9 pp 620—635
RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice
Figure 8. RhTFAM treatment improves learning and memory in aged mice. (A) Effects of rhTFAM and vehicle on latency to platform on during the seven days of Morris Water Maze training in aged (21-22 month old) mice. RhTFAM treatment significantly improved latency to platform (p<.05 by paired t-test). One and fifteen days after training, the platform was removed and mice were tested to determine recall of the position of the platform. RhTFAM treated aged mice spent significantly more time (B) in the platform zone as well as entering the zone more often (C) than did vehicle treated aged mice, * p<.05 by paired t-test.