Research Paper Volume 4, Issue 9 pp 620—635

RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice

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Figure 7. RhTFAM treatment improves State 3 mitochondrial respiration in brain, heart and skeletal muscle. Effects of rhTFAM treatment on state 3 (+ADP) respiration in mitochondrial preparations from brain, heart and muscle in 21 month old mice treated weekly with rhTFAM or buffer CTL, following addition of substrates for Complex I (CI) or Complex IV (CIV). * p<0.05 by paired t-test.