Accelerated <i>in vivo</i> epidermal telomere loss in Werner syndrome

Naoshi Ishikawa; Ken-Ichi Nakamura; Naotaka Izumiyama-Shimomura; Junko Aida; Akio Ishii; Makoto Goto; Yuichi Ishikawa; Reimi Asaka; Masaaki Matsuura; Atsushi Hatamochi; Mie Kuroiwa; Kaiyo Takubo

doi:doi:10.18632/aging.100315

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Research Paper Volume 3, Issue 4 pp 417—429

Accelerated in vivo epidermal telomere loss in Werner syndrome

Figure 4. Scatter plot analysis of TRF lengths in muscle samples from WS patients and controls. Multiple regression analysis yielded a regression line for the 4 WS patients (Y = 14.6 − 0.010X (age) − 2.6 (WS group: 1); in red) and a regression line for the non-WS control subjects (n = 14), (Y = 14.6 − 0.010X (age) − 2.6 (control group: 0); control line in black).