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Figure 2
Figure 2.Cyclophilin D is acetylated at K166(A) Representative m/z spectrum of peptide TDWLDG-AcK-HVVFGHVK obtained from mass spectrometry analyses of Flag-purified mouse Cyclophilin D. (B) Sequence of Cyclophilin D (Mus musculus). Location of the identified acetylation site. (Peptide: blue; acetylated Lysine: red). (C) Protein sequence alignment of CypD from Homo sapiens, Mus musculus, Danio rerio, Saccharomyces cerevisiae. Lysine 166 is marked in red.
Figure 2 — Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy | Aging