Figure 1.Models of aging pathways. (A) A scenario in which DNA
damage acts as a causal trigger for aging. (B) A scenario in which
chromatin structure acts as a causal trigger for aging. Feedback loops,
which are likely to exist between most individual events, are not shown for
simplicity. (C) Chromatin structure and DNA damage pathways act in
an integrated fashion with a multitude of other cellular process to form a
network of aging processes.
