Figure 4.Neuronal
degeneration is accelerated in per01mutants compared to
CSp and flies with restored per function (per01{per+}) on day 50. (A) Mean number of
vacuoles (with SEM) representing neuronal degeneration was significantly
higher in per01mutants compared with wild type CSp
and flies with rescued per. Bars with different superscripts are
significantly different at p<0.05, data based on 10-15 heads for each
genotype. (B-D) Photomicrographs of representative brain sections of
CSp, per01, and per01{per+}
males. Arrows point to vacuolization.