Figure 1.Lifespan of per01and CSpD. melanogaster in normoxia and following 24h
hyperoxia at different ages (marked by arrow in B-D). (A)
In normoxia, there was no significant difference in mean survival curves
(p=0.23) (B) Hyperoxia on day 5 did not significantly affect
longevity or survival curves (p=0.12) (C) Hyperoxia on day 20
resulted in a significant reduction (p<0.05) in average survival of per01flies compared to CSp with significant (p<0.0001)
difference in survival curves. (D) Hyperoxia on day 35 resulted in
more significant reduction (p<0.001) in average lifespan in per01flies compared to CSp and significant difference in survival
curves (p<0.0001). Males with rescued per function (per01{per+}) treated with hyperoxia on day 35 had average
lifespan similar to CSp but significantly different (p<0.001)
from per01mutants.
