Research Paper Volume 1, Issue 2 pp 212—218

Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells

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Figure 2. Endogenous γ-H2AX foci in interphase cells of five human tumor cell lines. (A) Images of endogenous γ-H2AX foci (green) in untreated HeLa, HCT116, M059K, SiHa and SW756 cells. DAPI staining (blue) indicates DNA. (B) Average numbers of γ-H2AX foci per cell in three independent experiments (Expt 1-3) with high SDs (n is at least 70 cells counted in each experiment), and average of averages from these experiments (n=3). (C) Fractions of cells in the five tumor cell populations with the noted numbers of γ-H2AX foci.