Figure 6 — Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53

Research Paper|Volume 1, Issue 1|pp. 89–108

Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53

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Figure 6.GeneChip expression of 13 reported E2F1-regulated genes that were repressed by knockdown of either siHdmX or siHdm2. Y-axis represents the average fold change (log₂) for each of the genes in the indicated siRNA transfections relative to siCon (X-axis, conditions labeled at the top of the chart).