Retraction Volume 16, Issue 8 pp 7507
Retraction of: PHTF2 regulates lipids metabolism in gastric cancer
- 1 Department of Oncology, People’s Hospital of Rizhao, Rizhao 276800, Shandong Province, China
Received: December 29, 2023 Accepted: April 20, 2024 Published: April 30, 2024
https://doi.org/10.18632/aging.205842How to Cite
Copyright: © 2024 Chi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This article has been retracted: Aging has completed its investigation of this paper. We found that the immunohistochemistry images in Figure 2H, showing PHTF2 expression pattern in gastric cancer tissues, were previously published in an unrelated paper from a different lab studying PBX1 protein in clear cell renal carcinoma [1]. We also found that the image of immunofluorescence staining in Figure 3I, representing the neutral lipids content detected by double staining with BODIPY 493/503 dye in GCIY/shACSL1 gastric cancer cells, is a duplication of a BODIPY image of Zebrafish liver cells from an unrelated paper [2]. In addition, the colony formation images shown in Figure 4B are the same as in an earlier published paper from an unrelated team of authors studying bladder cancer [3]. The authors were informed about the results of the Aging investigation and all authors agreed that the article should be retracted.
References
- 1. Wei X, Yu L, Li Y. PBX1 promotes the cell proliferation via JAK2/STAT3 signaling in clear cell renal carcinoma. Biochem Biophys Res Commun. 2018; 500:650–57. https://doi.org/10.1016/j.bbrc.2018.04.127 [PubMed]
- 2. Wang J, Han SL, Lu DL, Li LY, Limbu SM, Li DL, Zhang ML, Du ZY. Inhibited Lipophagy Suppresses Lipid Metabolism in Zebrafish Liver Cells. Front Physiol. 2019; 10:1077. https://doi.org/10.3389/fphys.2019.01077 [PubMed]
- 3. Li Y, Zhang X, Zhou X, Zhang X. LHPP suppresses bladder cancer cell proliferation and growth via inactivating AKT/p65 signaling pathway. Biosci Rep. 2019; 39:BSR20182270. https://doi.org/10.1042/BSR20182270 [PubMed]