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Research Paper|Volume 15, Issue 6|pp 1890—1917

The study of antecedent clinical manifestations of hypertensive heart disease in cohort of hypertension

Qian Li1, Na Li2, Xiao Liang3, Yanjie Liu4, Li Chen5, Huimin Lao6, Sheng Wei7,8, Jun Xiao9, Xiaoqiang Qi9,10
  • 1The American Academy of Tradition Chinese Medicine Inc. Roseville, MN 55113, USA
  • 2Qingdao Fifth People’s Hospital, Qingdao 266002, Shandong, China
  • 3Saint Mary’s University of Minnesota, Minneapolis, MN 55404, USA
  • 4Department of Neck-Shoulder-Lumbocrural Pain Treatment, Yantai Hospital of Traditional Chinese Medicine, Yantai 264013, Shandong, China
  • 5Department of Science and Education, Shandong Provincial Third Hospital, Jinan 250031, Shandong, China
  • 6Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan 250011, Shandong, China
  • 7Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong, China
  • 8Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong, China
  • 9The Macrohard Institute of Health, Roseville, MI 48066, USA
  • 10University of Missouri-Columbia, Columbia, MO 65212, USA
* Equal contribution
Received: March 19, 2021Accepted: August 17, 2021Published: February 19, 2023
https://doi.org/10.18632/aging.204510

Copyright: © 2023 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Hypertensive heart disease presents increasing morbidity and mortality worldwide, however, the data about its epidemics and its specific symptoms in hypertension patients is scarce. To assess the frequency and correlated symptoms of hypertensive heart disease, 800 hypertension patients were randomly recruited for this study per the guidelines of the American College of Cardiology. The diagnosis of heart disease and its typical symptoms (palpitation and angina) were analyzed for the frequency of hypertensive heart disease in hypertension cohort. Cross-tabulation analysis was used to study the correlation between psychiatric indexes (annoy, amnesia, irritableness, depression, anxiety, and fear) and palpitation, the correlation between physical disorders (backache, lumbar debility, and numbness of limbs) and palpitation, and the correlation between symptoms (dizziness, daze, headache, and tinnitus) and palpitation presented in hypertensive patients. It was found that around half of patients suffered hypertensive heart disease, which correlated to certain physical and mental symptoms. Significant correlation exists between palpitation and annoy / amnesia. Significant correlation exists between palpitation and backache / lumbar debility / numbness of limbs; and significant correlation exists between palpitation and dizziness / daze / headache / tinnitus. These results provide clinical insights into the modifiable antecedent clinical conditions which are risk factors for hypertensive heart disease in elderly and will help improve early management of this disease.