Yinan Zheng1Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA, Mohamad Habes2,Biggs Institute Neuroimaging Core, Glenn Biggs Institute for Neurodegenerative Disorders, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA3Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA, Mitzi Gonzales2Biggs Institute Neuroimaging Core, Glenn Biggs Institute for Neurodegenerative Disorders, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA, Raymond Pomponio3Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA, Ilya Nasrallah3Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA, Sadiya Khan1,Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA4Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA, Douglas E. Vaughan5Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA, Christos Davatzikos3Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA, Sudha Seshadri2,Biggs Institute Neuroimaging Core, Glenn Biggs Institute for Neurodegenerative Disorders, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA6Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA, Lenore Launer7Laboratory of Epidemiology and Population Science, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA, Farzaneh Sorond8Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA, Sanaz Sedaghat9Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA, Derek Wainwright10Departments of Neurological Surgery, Medicine-Hematology and Oncology, Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA, Andrea Baccarelli11Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY 10032, USA, Stephen Sidney12Kaiser Permanente Division of Research, Oakland, CA 94612, USA, Nick Bryan13Department of Diagnostic Medicine, Dell Medical School, University of Texas at Austin, Austin, TX 78712, USA, Philip Greenland1Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA, Donald Lloyd-Jones1Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA, Kristine Yaffe14,Departments of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA 94143, USA15,Department of Neurology University of California, San Francisco, CA 94143, USA16,Department of Epidemiology and Biostatistics, University of California San Francisco, CA 94143, USA17San Francisco VA Medical Center, San Francisco, CA 94143, USA, Lifang Hou1Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
- 1Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
- 2Biggs Institute Neuroimaging Core, Glenn Biggs Institute for Neurodegenerative Disorders, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
- 3Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
- 4Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
- 5Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
- 6Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA
- 7Laboratory of Epidemiology and Population Science, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
- 8Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
- 9Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
- 10Departments of Neurological Surgery, Medicine-Hematology and Oncology, Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
- 11Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY 10032, USA
- 12Kaiser Permanente Division of Research, Oakland, CA 94612, USA
- 13Department of Diagnostic Medicine, Dell Medical School, University of Texas at Austin, Austin, TX 78712, USA
- 14Departments of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA 94143, USA
- 15Department of Neurology University of California, San Francisco, CA 94143, USA
- 16Department of Epidemiology and Biostatistics, University of California San Francisco, CA 94143, USA
- 17San Francisco VA Medical Center, San Francisco, CA 94143, USA
* Equal contribution
# Co-senior author
