Aging and Circadian Disruption: Causes and Effects

Steven A. Brown; Karen Schmitt; Anne Eckert

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Research Perspective Volume 3, Issue 8 pp 813—817

Aging and Circadian Disruption: Causes and Effects

Steven A. Brown^1, , Karen Schmitt^2, , Anne Eckert^2, ,

¹ Department of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
² Neurobiology Laboratory for Brain Aging and Mental Health, Psychiatric University Clinics Basel, Basel, Switzerland

Received: July 9, 2011 Accepted: July 27, 2011 Published: August 22, 2011

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Copyright: © 2011 Brown et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The relationship between aging and daily “circadian” behavior in humans is bidirectional: on the one hand, dysfunction of circadian clocks promotes age-related maladies; on the other, aging per se leads to changes and disruption in circadian behavior and physiology. For the latter case, recent research suggests that changes to both homeostatic and circadian sleep regulatory mechanisms may play a role. Could hormonal changes be in part responsible?

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Featured Nobel Articles

Research Perspective Volume 3, Issue 8 pp 813—817

Aging and Circadian Disruption: Causes and Effects

Steven A. Brown^1, , Karen Schmitt^2, , Anne Eckert^2, ,

Received: July 9, 2011 Accepted: July 27, 2011 Published: August 22, 2011

Abstract

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Featured Nobel Articles

Research Perspective Volume 3, Issue 8 pp 813—817

Aging and Circadian Disruption: Causes and Effects

Steven A. Brown1, , Karen Schmitt2, , Anne Eckert2, ,

Received: July 9, 2011 Accepted: July 27, 2011 Published: August 22, 2011

Cite this Article

How to cite

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Abstract

Corresponding Author

Keywords

Steven A. Brown^1, , Karen Schmitt^2, , Anne Eckert^2, ,