Figure 4.hTERT progressively lengthens telomeres with passages in human and in non-human primate cells. (A, B) Telomere length analysis by HT-qFISH in human BJ, human lung fibroblasts, non-human primate lung fibroblasts, porcine lung fibroblasts, canine lung fibroblasts, rabbit lung fibroblasts, rat lung fibroblasts, and in Tert−/− mouse embryonic fibroblasts transduced either with pLOC-empty or pLOC-hTERT. Cells were analyzed at 10 (A), 40, or 80 (B) days post-infection (dpi). The assays were performed in 3–4 replicas. The bars represent the mean value, and the error bars the standard error. The statistical significance was calculated by an unpaired Student’s t-test (two-tailed).
