Figure 3.hTERT is active by TRAP in human, non-human primate, porcine, rabbit, and rat cells, and inactive in canine and mouse cells. Telomerase Repeat Addition Protocol (TRAP) in cells transduced either with pLOC-empty or pLOC-hTERT. Abbreviations: IC: internal control for the PCR efficiency; TS: telomerase substrate. The number of nucleotides (nt) of IC, TS and the first TRAP amplified fragment are indicated.