Research Paper Volume 17, Issue 2 pp 524—549

Figure 6. Microbial metabolism of tryptophan to kynurenine may be affected by age and mt-haplotype in female rats. Plasma tryptophan metabolites from male (A) and female (B) OKC-HET^B (blue boxes) and OKC-HET^W (red boxes) adult (9-months) or old (26-months) rats are shown. The box plots display the 1st and 3rd quartiles and a horizontal line at the median, and the whiskers display minimum and maximum values. The data were collected from 5 randomly selected rats per group, and the values significantly different by FDR ^*q < 0.05 or values marginally significant by Fisher’s LSD ^◊p < 0.05 are shown.