Research Paper Volume 17, Issue 2 pp 308—328
Cysteinyl leukotriene receptor 1 modulates retinal immune cells, vascularity and proteolytic activity in aged mice
Figure 1. Gene expression profile in the retinas of young untreated and vehicle- and MTK-treated old mice. The mRNA levels of (A) Alox5ap, (B) Cysltr1, (C) H2-Aa, (D) Trem2, (E) TSPO, (F) Angpt1, (G) Angpt2, (H) Nup62, (I) Prkcd, (J) Sgk1, (K) Sirt1, (L) Becn1, (M) Lamp1, (N) Lamp2, (O) Map1lc3b and (P) Sqstm1 are represented as bar graphs and scatter plots ± SDs, n = 3–7. Two-way ANOVA (main factors: group and sex) followed by a Dunnett multiple comparison test. ####p < 0.0001, ###p < 0.001, ##p < 0.01, #p < 0.05, young control group vs. old vehicle-treated group; **p < 0.01, old MTK-treated group vs. old vehicle-treated group.