Priority Research Paper Volume 16, Issue 22 pp 13452—13504
Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution
Figure 2. Meta-analysis of brain cell-type fractions with age. (A) Forest plots of associations between brain cell-type fractions and age, for 7 brain cell-types (Abbreviations: ExN: excitatory neurons; InN: inhibitory neurons; Oligo/OPC: oligodendrocytes/oligo precursor cells; Micro: microglia; Astro: astrocytes, Stromal; Endo: endothelial) across 13 independent DNAm datasets. Number of samples in each cohort is given in brackets. P-values from a Fixed and Random Effects models are also given. Heterogeneity statistics and P-values of heterogeneity are given above each plot. (B) Effect sizes and P-values from the Random Effects meta-analysis model.