Research Paper Advance Articles
Treadmill intervention attenuates motor deficit with 6-OHDA-induced Parkinson’s disease rat via changes in lipid profiles in brain and muscle
Figure 2. Exercise rescued the 6-OHDA-mediated reduction of dopaminergic neurons in the substantia nigra pars compacta (SNc) after 10 weeks of exercise treatments. (A) A representative of the immunohistochemical staining for TH (dopaminergic neuron marker) in the striatum. (B) Quantitative analysis of the number of TH-positive cells in the striatum. (C) A representative of the immunohistochemical staining for the TH in SNc. (D) Quantitative analysis of the TH-positive cells in the SNc. Data are presented as the mean ± standard deviation (SD) (n = 5/group). Significance was determined by a one-way ANOVA with Tukey’s post-hoc test. *p < 0.05; **p < 0.01; ***p < 0.001. Control (C), Parkinson’s disease (PD), 6-hydroxy dopamine (6-OHDA).