Research Paper Advance Articles
Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing
Figure 1. Decreased senescence markers in aged skin treated with topical ABT-263. (A) Relative p16 and p21 expression in whole skin after 5 days of ABT-263 (N=5) vs. DMSO treatment (N=5). (B) SA-β-gal positive cells (green) and quantification of percentage of positive cells. (C) p21 staining and quantification of percentage of positive cells. *p<0.05, **p<0.01, ***p<0.001, t-test.