Figure 3 — Supplementation with nicotinamide limits accelerated aging in affected individuals with cockayne syndrome and restores antioxidant defenses

Research Paper|Volume 16, Issue 21|pp. 13271–13287

Supplementation with nicotinamide limits accelerated aging in affected individuals with cockayne syndrome and restores antioxidant defenses

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Figure 3.The level of oxidative stress-related gene expression after nicotinamide stimulation. The histograms represent fold-changes in genes up-or downregulated in CS-A, CS-B, elderly group and young healthy donors’ group normalized to non-treated control conditions of each group. (A) PRDX3, (B) FOXM1, (C) NQO1 and (D) ALOX12.