Research Paper Volume 16, Issue 21 pp 13225—13236

Adolescents and young adults with sickle cell disease exhibit accelerated aging with elevated T-cell p16INK4a expression

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Figure 2. Expression of p16 by age. Scatterplot of p16 expression by age demonstrates that the SCD group generally has higher p16 expression across the entire age range. The youngest SCD participant has higher p16 expression than all the comparators.