Research Paper Volume 16, Issue 21 pp 13356—13370
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway
Figure 6. Phosphorylated RXRA interacted with TRAF2 to downregulate TRAF2 protein. (A) The interaction between RXRA and TRAF2 was detected by Co-IP analysis. (B) The protein expression of TRAF2 in mice of the sham and AMI groups was detected with Western blotting. (C) H9C2 cells were transfected with sh-RXRA or sh-NC, and then treated with OGD, and the protein expression of TRAF2 was detected with Western blotting. (D) H9C2 cells were transfected with RXRA overexpression vector (pc-RXRA) and control (vector), and then treated with OGD and/or Bex. The protein expression of TRAF2 was detected with Western blotting. **P < 0.01.